Nephrology Guideline Database

Guideline Target Rationales

As a first step towards its mission statement to promote “coordination, collaboration, and integration of initiatives to develop and implement clinical practice guidelines”, KDIGO convened in April 2006 a meeting of the organizations who have developed the five guidelines currently listed and compared on the KDIGO webpage. At this meeting, it was decided to establish a Liaison Task Force composed of a representative from each organization to examine the variations in recommended targets and provide a brief justification for each of the apparent differences.

The Liaison Task Force is currently composed of Robert Mactier (RA-UK); Martin Gallagher (CARI-Australia); Michael Rocco/Adeera Levin (KDOQI-USA); Marcello Tonelli (CSN-Canada); James Tattersall (EBPG-Europe); and Raymond Vanholder, chair.

The first five topics selected by the committee to launch this initiative are: target hemoglobin; Kt/Vurea for hemodialysis; Kt/Vurea for peritoneal dialysis; time of referral to a nephrologist; and preferred vascular access for hemodialysis. (each of these five can be made into a link to the tables comparing them) Over time, the Liaison Task Force will examine systematically all the tables comparing recommended targets and provide a justification for each on an ongoing basis as the guidelines are updated.

Raymond Vanholder Chair, Liaison Task Force

The target rationales for the following topics are now available:

Rationale for Guideline Hemoglobin Targets

Rationale for Guideline Kt/V urea Targets for Hemodialysis

Rationale for Guideline Kt/V urea Targets for Peritoneal Dialysis

Rationale for Guideline for “Time of referral to Nephrologists”

Rationale for Guideline for “Preferred Vascular Access”

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