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To improve the care and outcomes of kidney disease
patients worldwide through promoting coordination,
collaboration and integration of initiatives to develop
and implement clinical practice guidelines.

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Topic:
  Target CO2 / bicarbonate
Guideline
Recommendation :
Evidence: Notes:
CARI-Australia
October 2004
Oral bicarbonate should be given to reach bicarbonate levels above 22 mmol/L (non-dialysed)

21. Acidosis in predialysis patients
P 1 of 6 PDF pages

Evidence III
Each Na Bicarbonate tablet (1 g?) contains 10 mmol Na.
Na Bicarbonate to be preferred to Na Citrate with intake Aluminum phosphate binders
CSN-Canada      
EBPG-Europe      
KDOQI-US
October 2004
Serum CO2 should be maintained at 22 mmol/L, if necessary with supplemental alkali salts Guidelines: Bone Metabolism and Disease in Chronic Kidney Disease
Guideline 15: Metabolic acidosis
 
See also table 32 for intervals of measurements
Evidence
Stages 3, 4 and 5
Stage 3: at least every 12 mths
Stage 4: at least every 3 mths
Stage 5 (non-dialysis): at least every 3 mths
Stage 5 (dialysis): at least every mth
UK-Guidelines
August 2002
- HD: Serum bicarbonate at start of a HD-session should be between 20 and 26 mmol/L
- PD: Serum bicarbonate between 25 and 29 mmol/L

5. Hemodialysis and peritoneal dialysis:  Nutritional and biochemical standards
P 96 of 204 PDF pages

Evidence levels C and B




Measurement with minimal delay after venepuncture