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Table 6: Mode of guideline scoring,
depending on the origin |
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CARI-Guidelines |
• I : Evidence obtained from a systematic review of all relevant
RCT’s
• II : Evidence obtained from at least one properly designed RCT
• III: Evidence obtained from comparative studies (cohort, case
control)
• IV: Evidence obtained from case series |
I, II, III, IV equals KDIGO
evidence levels |
| CSN-Canada |
• I : RCT which demonstrates a statistically significant
difference in at least one important outcome or a RCT of
adequate size to exclude a 25% difference in relative risk with
80% power given the observed results.
• II : CT which does not meet the level I criteria
• III : A non-randomised trial with contemporaneous controls
selected by some systematic method.
• IV : A before-after study of case series (at least 10
patients) with historical controls.
• V : Case series (at least 10) without controls
• VI : Case report (<10 pts) |
I-II equals I-II KDIGO III-VI equals III-IV KDIGO |
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EBPG-Europe |
According to the categories of the US Department of Health and
Social Services(1992)
• A : Evidence from at least one prospective randomised
controlled trial or from meta-analyses of several controlled
trials
• B : Evidence from qualitatively satisfactory but uncontrolled
open studies
• C : Opinions of consensus groups such as the NKF-DOQI Work
Group |
A equals I-II KDIGO
B equals III-IV KDIGO
C equals opinion KDIGO |
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KDOQI-US |
• Evidence
• Opinion |
Evidence equals I-II-III or IV KDIGO |
| UK-Guidelines |
The term ‘standard’ is used when the available evidence is
strong or for key ‘good practice’ statements
Recommendation is used where the available evidence is weaker
and for other ‘good practice’ statements.
• A : Evidence from randomised controlled trials or
meta-analysis of several controlled trials
• B : Well conducted trials but no randomised trials
• C : Expert opinions |
A equals I-II KDIGO
B equals III-IV KDIGO
C equals Opinion KDIGO |
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Abbreviations: RCT or randomised controlled trial
CT or controlled trial
Rating KDIGO system: I = Meta-analysis
II = Controlled randomised study
III= Case controls or observational study
IV = Case reports
Opinion |
