Speaker Center

KDIGO Controversies Conference: Coordination of Clinical Practice Guidelines for Anemia in CKD, New York, October 2007 (Position Statement Pending)

In preparation for the meeting the conference co-chairs (Francesco Locatelli and Allen Nissenson) worked together with the KDIGO co-chairs (Norbert Lameire, Kai-Uwe Eckardt, and Garabed Eknoyan) to define the issues to be addressed; evaluate on-going clinical trials in the treatment of anemia in CKD, cancer, and cardiovascular disease; and compile the participant list. Invited participants included the leadership of five principal guideline development organizations (CARI, CSN, EBPG, KDOQI, UK-RA); their experts in the development and implementation of guidelines, methodologists, specialists in quality of life measurement in CKD, and other investigators in the field.

The meeting started with a plenary session during which presentations provided a comparison of the methodology and recommended hemoglobin targets of the five principal guidelines published in English; the evidence base of the recommendations of the KDOQI 2007 update; an overview of the status of new erythropoeisis stimulating agents (ESA) and iron supplements; the design and timeline of the ongoing TREAT study, the merits and limitations of quality of life studies in CKD; and the need for coordination of future guidelines on anemia in CKD. The participants then met in two breakout groups to address the topics covered and a number of specific questions designed to consider what we know, what we can do with what is known, and what we still need to know. The recommendations of each breakout groups were then presented by their respective leaders and rapporteurs (Rowan Walker, David Wheeler, Brendan Barrett, Francesco Locatelli, and Allen Nissenson) to the entire group for discussion and refinement.

Click here to see the published position paper from the conference proceedings

Click here for the complete description and agenda from the conference

Click here for the roster of conference participants

Conference Plenary Session Presentations:
Comparison of evidence review process for five primary global anemia guidelines
Presenter: Alison MacLeod

Comparison of recommendations from five primary global anemia guidelines
Presenter: Ray Vanholder

KDOQI 2007 Update on hemoglobin target: Recommendation and evidence base
Presenter: Kai-Uwe Eckardt

New data and developments since publication of latest guidelines

• Erythropoietin Stimulating Agents
  Presenter: Iain MacDougall

• Iron Supplementation
  Presenter: Rajiv Agarwal

Anemia and Cardiac Disease
Presenter: Scott Solomon

Anemia and quality of life (QOL) measurements

• Validity of QOL instruments as an outcome measure
  Presenter: Dennis Revicki

• Studies on QOL and anemia – What does it show?
  Presenter: Paul Kimmel

Coordination of future anemia guidelines - what can be done?
Presenter: Jeffrey Berns