KDIGO Publications
Clinical Guide to Bone and Mineral Metabolism in CKD
Olgaard, K (ed), 1st Edition, New York, National Kidney Foundation, 2006. (Order here)
Description: Over the last decade, there have been significant advances in the field of bone and mineral metabolism in patients with chronic kidney disease (CKD). Advances in the basic sciences of bone and vascular biology have led to an improved understanding of vascular pathology and calcification, and we have gained an important understanding and appreciation of the extraskeletal manifestations of mineral metabolism. Our diagnostic capabilities have been enhanced through the development of innovative techniques in radiographic imaging and new assay methodologies for PTH and other bone markers. New vitamin D analogs and phosphate binders, as well as calcimimetics, have been added to our therapeutic regimens.
The Clinical Guide was developed to serve the needs of all those who provide care to CKD patients, including nephrologists, nephrology trainees, nephrology nurses and dieticians, cardiologists, endocrinologists, primary care providers, and house officers.
The Clinical Guide content covers:
- basic bone and mineral physiology;
- diagnostic approaches, including bone biopsy, imaging techniques and bone biomarkers;
- pathophysiology and clinical manifestations of secondary hyperparathyroidism, renal osteodystrophy, and extraskeletal calcification;
- therapeutic options to manage bone and mineral disorders;
- unique aspects of bone and mineral metabolism in special populations, such as children, patients with hypogonadism, and kidney transplant recipients; and
- epidemiologic data linking abnormalities of bone and mineral metabolism to morbidity and mortality.
